Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene.

@article{Takahashi1988DevelopmentallyRE,
  title={Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene.},
  author={Mika Takahashi and Yutaka Inaguma and Hiroshi Hiai and Fumiko Hirose},
  journal={Molecular and cellular biology},
  year={1988},
  volume={8 4},
  pages={1853-6}
}
We isolated and sequenced a cDNA clone of the human gene encoded by the 5' half of the ret transforming gene. The nucleotide sequence indicates that it encodes a protein with "finger" structures which represent putative metal- and nucleic acid-binding domains. Transcription of this gene was detected at high levels in a variety of human and rodent tumor cell lines, mouse testis, and embryos. In addition, a unique transcript was observed in testis RNA. When the expression of the unique transcript… CONTINUE READING
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