Developmentally regulated Drosophila gene family encoding the fork head domain.

  title={Developmentally regulated Drosophila gene family encoding the fork head domain.},
  author={Udo H{\"a}cker and Ueli Grossniklaus and W. J. Gehring and Herbert Jaeckle},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={89 18},
We have isolated seven Drosophila genes by means of low-stringency hybridization to a DNA probe containing the coding sequence for the protein domain shared by the rodent hepatocyte-enriched nuclear transcription factor HNF3A (alpha) and the product of the Drosophila region-specific homeotic gene fork head (fkh). The previously unreported genes encode a 110-amino acid conserved sequence, which we call the fork head (fkh) domain. Two of these fkh-domain-encoding genes ("FD genes") map to the… CONTINUE READING

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