Developmentally and transgene regulated nuclear processing of primary transcripts of chalcone synthase A in petunia.

@article{Metzlaff2000DevelopmentallyAT,
  title={Developmentally and transgene regulated nuclear processing of primary transcripts of chalcone synthase A in petunia.},
  author={Michael Metzlaff and M O'dell and Roger P Hellens and Richard B. Flavell},
  journal={The Plant journal : for cell and molecular biology},
  year={2000},
  volume={23 1},
  pages={63-72}
}
The introduction of chalcone synthase A transgenes into petunia plants can result in degradation of chalcone synthase A RNAs and loss of chalcone synthase, a process called cosuppression or post-transcriptional gene silencing. Here we show that the RNA degradation is associated with changes in premRNA processing, i.e. loss of tissue specificity in transcript cleavage patterns, accumulation of unspliced molecules, and use of template-specific secondary poly(A) sites. These changes can also be… CONTINUE READING
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