Developmentally and hormonally regulated CCAAT/enhancer-binding protein isoforms influence beta-casein gene expression.

@article{Raught1995DevelopmentallyAH,
  title={Developmentally and hormonally regulated CCAAT/enhancer-binding protein isoforms influence beta-casein gene expression.},
  author={Brian Raught and Warren S-L. Liao and Jeffrey M. Rosen},
  journal={Molecular endocrinology},
  year={1995},
  volume={9 9},
  pages={1223-32}
}
A highly conserved CCAAT/enhancer-binding protein (C/EBP)-binding site centered around -134 relative to the transcription start site in the rat beta-casein gene promoter is capable of interacting specifically with recombinant and mammary gland C/EBP proteins. Western blot analysis indicates that C/EBP levels change dramatically throughout mammary gland development. C/EBP alpha expression is barely detectable in mammary glands from virgin and pregnant animals but is expressed at high levels… CONTINUE READING

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