Developmentally acquired PKA localisation in mouse oocytes and embryos.

@article{Webb2008DevelopmentallyAP,
  title={Developmentally acquired PKA localisation in mouse oocytes and embryos.},
  author={Rachel J. Webb and Lorna E. Tinworth and Geraint M. H. Thomas and Manuela Zaccolo and John R. Carroll},
  journal={Developmental biology},
  year={2008},
  volume={317 1},
  pages={36-45}
}
Localisation of Protein Kinase A (PKA) by A-Kinase Anchoring Proteins (AKAPs) is known to coordinate localised signalling complexes that target cAMP-mediated signalling to specific cellular sub-domains. The cAMP PKA signalling pathway is implicated in both meiotic arrest and meiotic resumption, thus spatio-temporal changes in PKA localisation during… CONTINUE READING