Developmental trajectories of symptom severity and adaptive functioning in an inception cohort of preschool children with autism spectrum disorder.

@article{Szatmari2015DevelopmentalTO,
  title={Developmental trajectories of symptom severity and adaptive functioning in an inception cohort of preschool children with autism spectrum disorder.},
  author={Peter Szatmari and Stelios Georgiades and Eric K Duku and Teresa Ann Bennett and Susan E. Bryson and E. J. Fombonne and Pat Mirenda and Wendy Roberts and Isabel M. Smith and Tracy Vaillancourt and Joanne Volden and Charlotte Waddell and Lonnie Zwaigenbaum and Mayada Elsabbagh and Ann P. Thompson},
  journal={JAMA psychiatry},
  year={2015},
  volume={72 3},
  pages={276-83}
}
IMPORTANCE Symptom severity and adaptive functioning are fundamental domains of the autism spectrum disorder (ASD) phenotype. To date, the longitudinal association between these 2 domains has not been examined. OBJECTIVE To describe the developmental trajectories of autistic symptom severity and adaptive functioning in a large inception cohort of preschool children with ASD. DESIGN, SETTING, AND PARTICIPANTS The sample consisted of 421 newly diagnosed preschool children with ASD 2 to 4… CONTINUE READING
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