Developmental toxicity of dinitroaniline herbicides in rats and rabbits. I. Trifluralin.

@article{Byrd1995DevelopmentalTO,
  title={Developmental toxicity of dinitroaniline herbicides in rats and rabbits. I. Trifluralin.},
  author={Richard Byrd and Joseph Markham and John Emmerson},
  journal={Fundamental and applied toxicology : official journal of the Society of Toxicology},
  year={1995},
  volume={26 2},
  pages={181-90}
}
The potential developmental toxicity of trifluralin was evaluated in rats and rabbits. Pregnant rats and rabbits were dosed once daily by gavage on Gestation Days 6-15 and 6-18, respectively. Doses for rats were 0, 100, 225, 475, or 1000 mg/kg; doses for rabbits were 0, 100, 225, or 500 mg/kg. Cesarean sections were performed on rats and rabbits on Gestation Days 20 and 28, respectively. In rats, maternal toxicity was indicated in the 475 and 1000 mg/kg treatment groups by depression of body… CONTINUE READING