Developmental timeframes for induction of microgyria and rapid auditory processing deficits in the rat.

@article{Threlkeld2006DevelopmentalTF,
  title={Developmental timeframes for induction of microgyria and rapid auditory processing deficits in the rat.},
  author={Steven W. Threlkeld and Melissa M McClure and Glenn D. Rosen and Roslyn Holly Fitch},
  journal={Brain research},
  year={2006},
  volume={1109 1},
  pages={22-31}
}
Induction of a focal freeze lesion to the skullcap of a 1-day-old rat pup leads to the formation of microgyria similar to those identified postmortem in human dyslexics. Rats with microgyria exhibit rapid auditory processing deficits similar to those seen in language-impaired (LI) children, and infants at risk for LI and these effects are particularly marked in juvenile as compared to adult subjects. In the current study, a startle response paradigm was used to investigate gap detection in… CONTINUE READING

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