Developmental thyroid hormone disruption: prevalence, environmental contaminants and neurodevelopmental consequences.

@article{Gilbert2012DevelopmentalTH,
  title={Developmental thyroid hormone disruption: prevalence, environmental contaminants and neurodevelopmental consequences.},
  author={Mary E. Gilbert and Joanne Rovet and Zupei Chen and Noriyuki Koibuchi},
  journal={Neurotoxicology},
  year={2012},
  volume={33 4},
  pages={842-52}
}
Thyroid hormones (TH) are critical for growth and development and particularly brain development. There are numerous environmental agents that lead to marginal reductions of circulating TH. Although it is clear that severe developmental hypothyroidism is profoundly detrimental to neurodevelopment, there is less information regarding the consequences of modest degrees of thyroid. The impact of low level TH disruptions induced by environmental contaminants has not been defined. This paper is a… CONTINUE READING
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