Developmental switch of intestinal antimicrobial peptide expression

Abstract

Paneth cell-derived enteric antimicrobial peptides provide protection from intestinal infection and maintenance of enteric homeostasis. Paneth cells, however, evolve only after the neonatal period, and the antimicrobial mechanisms that protect the newborn intestine are ill defined. Using quantitative reverse transcription-polymerase chain reaction… (More)
DOI: 10.1084/jem.20071022

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