Developmental restoration of LTP deficits in heterozygous CaMKIIα KO mice.

Abstract

The Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a major mediator of long-term potentiation (LTP) and depression (LTD), two opposing forms of synaptic plasticity underlying learning, memory and cognition. The heterozygous CaMKIIα isoform KO (CaMKIIα+/-) mice have a schizophrenia-related phenotype, including impaired working memory. Here, we… (More)
DOI: 10.1152/jn.00518.2016

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Cite this paper

@article{Goodell2016DevelopmentalRO, title={Developmental restoration of LTP deficits in heterozygous CaMKIIα KO mice.}, author={Dayton J. Goodell and Tim A. Benke and K. Ulrich Bayer}, journal={Journal of neurophysiology}, year={2016}, volume={116 5}, pages={2140-2151} }