Developmental regulation of synaptotagmin I, II, III, and IV mRNAs in the rat CNS.

@article{Berton1997DevelopmentalRO,
  title={Developmental regulation of synaptotagmin I, II, III, and IV mRNAs in the rat CNS.},
  author={Fulvia Berton and C{\'e}cile Iborra and J. A. Boudier and Michael Seagar and B Marqu{\`e}ze},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1997},
  volume={17 4},
  pages={1206-16}
}
Synaptotagmin I is an abundant synaptic vesicle protein that has an essential function in mediating Ca2+-triggered neurotransmitter release. We have analyzed the distribution of four neural synaptotagmin isoforms during postnatal development of the rat CNS by in situ hybridization. Synaptotagmin I, II, III, and IV genes have distinct patterns of spatiotemporal expression except in cerebellum granule cells, where the four transcripts were detected during the formation of parallel fiber/Purkinje… CONTINUE READING