Developmental pharmacokinetics of lamivudine in 580 pediatric patients ranging from neonates to adolescents.


Lamivudine concentration-time courses were described for a very large range of ages to study the effects of body weight and maturation on lamivudine pharmacokinetics and to check the consistency of dosing recommendations. Lamivudine concentrations were monitored on a routine basis to produce concentrations similar to the known values in adults… (More)
DOI: 10.1128/AAC.01622-10


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