Developmental patterns of two alpha 1(IX) collagen mRNA isoforms in mouse.

  title={Developmental patterns of two alpha 1(IX) collagen mRNA isoforms in mouse.},
  author={Chia-Yang Liu and Bjorn Reino Olsen and Winston W. Y. Kao},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  volume={198 2},
Northern blot hybridization, reverse-transcription polymerase chain reaction (RT-PCR), and RNase protection assays were used to examine the expression of two alpha 1(IX) collagen mRNA species (long and short form) in developing mouse tissues. Furthermore, in situ hybridization was used to identify cells expressing the Col9a1 gene during eye development. The results indicate that during embryonic development eye and heart preferentially express the short form; lung and cartilage express the long… CONTINUE READING
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