Developmental parameters of cell death in the wing disc of Drosophila.

  title={Developmental parameters of cell death in the wing disc of Drosophila.},
  author={Marco Mil{\'a}n and Sonsoles Campuzano and Antonio Garc{\'i}a-Bellido},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={94 11},
Apoptotic cell death in wing imaginal discs takes place in single cells or small clusters of neighboring cells. These cells are distributed throughout the anlage at early stages and in recognizable territories at late larval and pupal stages. Apoptotic cells remain in the epithelium 2-4 h, prior to being engulfed in place by hemolymph cells. Experimentally induced apoptosis in single cells or territories is accompanied by nonautonomous death of adjacent cells and of cells further away in… CONTINUE READING

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