Developmental origins theory from prematurity to adult disease.

@article{Sullivan2008DevelopmentalOT,
  title={Developmental origins theory from prematurity to adult disease.},
  author={Mary C Sullivan and Katheleen Hawes and Suzy Barcelos Winchester and Robin June Miller},
  journal={Journal of obstetric, gynecologic, and neonatal nursing : JOGNN},
  year={2008},
  volume={37 2},
  pages={158-64}
}
Developmental Origins Theory has received little coverage in the nursing literature, even though it has received much attention in other sciences. The theory proposes that prenatal stress provokes adaptive changes in endocrine and metabolic processes that become permanently programmed and impact later adult health. This paper reviews the theory and describes the primary neuroendocrine mechanism of hypothalamic-pituitary-adrenal axis function. Supporting research evidence in preterm infant and… CONTINUE READING

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