Developmental origins of health and disease

  title={Developmental origins of health and disease},
  author={Jayant P. Shenai},
  journal={Journal of Perinatology},
Events during embryonic and fetal life as well as during early infancy may be a harbinger of disease in adulthood. Numerous examples can be cited to validate this contention. A fetus who fails to grow as a result of an adverse intrauterine environment may show a deficit of nephrons, predisposition of the nephrons to sclerosis from increased pressure in glomerular capillaries, and consequent development of hypertension in adult life. A fetus who has growth restriction with relative sparing of… CONTINUE READING


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