Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursors.

@article{Karsunky2005DevelopmentalOO,
  title={Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursors.},
  author={Holger Karsunky and Miriam Merad and Ines Mende and Markus G. Manz and Edgar G. Engleman and Irving L Weissman},
  journal={Experimental hematology},
  year={2005},
  volume={33 2},
  pages={173-81}
}
OBJECTIVE The aim of this study was to determine the lineage origin of interferon-alpha-producing cells (IPCs), also called plasmacytoid dendritic cells, in mice by evaluating the ability of common lymphoid (CLP) and myeloid (CMP) progenitors to give rise to IPCs. MATERIALS AND METHODS Sublethally irradiated C57Bl/6 mice were intravenously transplanted… CONTINUE READING