Developmental lead exposure alters methamphetamine self-administration in the male rat: acquisition and reinstatement.

@article{Rocha2008DevelopmentalLE,
  title={Developmental lead exposure alters methamphetamine self-administration in the male rat: acquisition and reinstatement.},
  author={Ang{\'e}lica Lacerda Rocha and Rodrigo Valles and Gerald R. Bratton and Jack R. Nation},
  journal={Drug and alcohol dependence},
  year={2008},
  volume={95 1-2},
  pages={23-9}
}
The rate of acquisition of drug self-administration and the return to drug seeking are important elements of the overall drug profile, and are essential factors in understanding risks associated with drug abuse. Experiment 1 examined the effects of perinatal (gestation/lactation) lead exposure on adult rates of acquisition of intravenous (i.v.) methamphetamine self-administration. Experiment 2 investigated the effects of perinatal lead exposure on drug-maintained responding in a reinstatement… CONTINUE READING