Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.

@article{Kleene1994DevelopmentalEO,
  title={Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.},
  author={Kenneth C. Kleene and M. Y. Wang and Michael Cutler and Christine Hall and D M Shih},
  journal={Molecular reproduction and development},
  year={1994},
  volume={39 4},
  pages={355-64}
}
The poly(A) binding protein (PABP), a conserved protein that binds to the 3' poly(A) tail on mRNAs in eukaryotic cells, has been implicated in the regulation of mRNA stability and translation. Two PABP cDNAs with different sequences were isolated from mouse testis cDNA libraries. The predicted amino acid sequence of one, PABP1, is nearly identical (98.9%) to human liver PABP, while 80% of the amino acids of the second, PABPt, are identical to mouse and human PABPs. Northern blots reveal that… CONTINUE READING

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