Developmental expression of mucin genes in the human respiratory tract.

  title={Developmental expression of mucin genes in the human respiratory tract.},
  author={C. S. J. Reid and Stephen Gould and Adrian H Harris},
  journal={American journal of respiratory cell and molecular biology},
  volume={17 5},
Mucin glycoproteins play a key role in the normal function of the airway epithelium. We examined the expression of mucin genes, MUC3, 4, 5AC, 5B, 6, 7, and 8 in human fetal tissues to establish the localization and age of onset of expression of each mucin gene during human development. We detected expression of MUC4, 5AC, 5B, and 7 in the mid-trimester airway epithelium but did not detect expression of MUC3, 6, or 8. MUC4 was expressed in the trachea and large airways in the majority of cells… CONTINUE READING

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