Developmental expression of an amn(+) transgene rescues the mutant memory defect of amnesiac adults.

@article{DeZazzo1999DevelopmentalEO,
  title={Developmental expression of an amn(+) transgene rescues the mutant memory defect of amnesiac adults.},
  author={James DeZazzo and Shuli Xia and Jesper Christensen and Klara Velinzon and Tim Tully},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1999},
  volume={19 20},
  pages={8740-6}
}
The Drosophila memory gene amnesiac (amn) has been proposed to encode a neuropeptide protein, which includes regions homologous to vertebrate pituitary adenylyl cyclase-activating peptide (PACAP; Feany and Quinn, 1995). Definitive experiments to link this gene to memory formation, however, have not yet been accomplished (Kandel and Abel, 1995). The experiments described here demonstrate that the putative amn transcript is involved in adult memory formation. With the use of a UAS-amn… CONTINUE READING

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