Developmental expression of GABA(A) receptor subunit mRNAs in individual hippocampal neurons in vitro and in vivo.

@article{BrooksKayal1998DevelopmentalEO,
  title={Developmental expression of GABA(A) receptor subunit mRNAs in individual hippocampal neurons in vitro and in vivo.},
  author={Amy R Brooks-Kayal and Huajun Jin and Margaret Price and Marc A. Dichter},
  journal={Journal of neurochemistry},
  year={1998},
  volume={70 3},
  pages={1017-28}
}
The GABA(A) receptor is a heterooligomeric protein complex composed of multiple receptor subunits. Developmental changes in the pattern of expression of 11 GABA(A) receptor subunits in individual rat embryonic hippocampal neurons on days 1-21 in culture and acutely dissociated hippocampal neurons from postnatal day (PND) 5 rat pups were investigated using the technique of single-cell mRNA amplification. We demonstrate that multiple GABA(A) receptor subunits are expressed within individual… CONTINUE READING