Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Gαs, a G-protein subunit genetically linked to schizophrenia

@article{Kelly2009DevelopmentalEF,
  title={Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Gαs, a G-protein subunit genetically linked to schizophrenia},
  author={Michele P Kelly and Joel M. Stein and Christopher G. Vecsey and Christopher G. Favilla and Xioaju Yang and S F Bizily and Michael F Esposito and Gary Wand and Stephen J. Kanes and Ted Abel},
  journal={Molecular Psychiatry},
  year={2009},
  volume={14},
  pages={398-415}
}
Schizophrenia is a widespread psychiatric disorder, affecting 1% of people. Despite this high prevalence, schizophrenia is not well treated because of its enigmatic developmental origin. We explore here the developmental etiology of endophenotypes associated with schizophrenia using a regulated transgenic approach in mice. Recently, a polymorphism that… CONTINUE READING