Developmental differences in the accumbal dopaminergic response to repeated ethanol exposure.

@article{Philpot2004DevelopmentalDI,
  title={Developmental differences in the accumbal dopaminergic response to repeated ethanol exposure.},
  author={Rex M. Philpot and Cheryl L. Kirstein},
  journal={Annals of the New York Academy of Sciences},
  year={2004},
  volume={1021},
  pages={422-6}
}
Recent research indicates that alcohol use/abuse is often initiated during the adolescent period and that brain reinforcement pathways (e.g., the mesolimbic dopamine [DA] pathway) are undergoing developmental transition. Our research focuses on the effects of ethanol administration on neural mechanisms associated with addiction in preadolescent (postnatal day [PND] 25), adolescent (PND 35, PND 45), and young adult (PND 60) animals. Using conditioned place preference (CPP) testing, we have shown… CONTINUE READING

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