Developmental deficits in social perception in autism: the role of the amygdala and fusiform face area

  title={Developmental deficits in social perception in autism: the role of the amygdala and fusiform face area},
  author={Robert T. Schultz},
  journal={International Journal of Developmental Neuroscience},
  • R. Schultz
  • Published 1 April 2005
  • Psychology, Biology
  • International Journal of Developmental Neuroscience

Examinations of social and non-social factors in the neurodevelopment of autism

Autism is a pervasive developmental disorder characterized by deficits in social and communication skills, as well as restricted interests and repetitive behaviors, with symptom onset by 3 years of

[Social cognition in autism. A survey of functional imaging studies].

The present review gives a systematic overview of the existing literature on functional imaging studies using experimental paradigms of social cognition, i.e. face discrimination, facial emotion recognition, and theory of mind in autistic disorders.

Neural endophenotypes of social behavior in autism spectrum conditions

The main objective is to highlight the current state of the field regarding theory of mind/empathy difficulties in ASC, and then to suggest distinct candidate neural endophenotypes that can bridge the gap between social behavior and genetic mechanisms.

The amygdala and the relevance detection theory of autism: an evolutionary perspective

It is proposed that the behavioral and social–emotional features of ASDs may be better understood in terms of a disruption in a “Relevance Detector Network” affecting the processing of stimuli that are relevant for the organism’s self-regulating functions.

The Neural Basis of Autism: A Review

Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition for which there is no known cause or cure. Autism is a highly variable disorder, the most prominent difficulties of which

A functional and structural study of emotion and face processing in children with autism

3 Autism Spectrum Disorders

Autism spectrum disorder (ASD) is an umbrella term that refers to a group of neurodevelopmental disorders characterized by impairments in social communication and a restricted range of interests and

Autism: A review for family physicians.

  • S. Karande
  • Psychology, Medicine
    Indian journal of medical sciences
  • 2006
Although there is currently no known cure for autism there is evidence to suggest that early intervention therapy can improve functioning of autistic children and judicious use of psychotropic drugs is necessary to manage associated aggression, hyperactivity, self-mutilation, temper tantrums.

The Interplay between Emotion and Cognition in Autism Spectrum Disorder: Implications for Developmental Theory

It is suggested that ASD is the developmental consequence of early emerging anomalies in how emotional responses to the environment modulate a wide range of cognitive processes including those that are relevant to navigating the social world.

Face processing in autism spectrum disorders: From brain regions to brain networks




Activation of the fusiform gyrus when individuals with autism spectrum disorder view faces

A dimensional classification of autism spectrum disorder by social communication domains.

The DSM-IV category of pervasive developmental disorder may be ideal for diagnosing "classic" autism, but it may be inadequate fordiagnosing less severe forms of the disorder.

The amygdala theory of autism

Face processing occurs outside the fusiform 'face area' in autism: evidence from functional MRI.

It appears that, as compared with normal individuals, autistic individuals 'see' faces utilizing different neural systems, with each patient doing so via a unique neural circuitry, suggesting that experiential factors do indeed play a role in the normal development of the FFA.

Neural correlates of facial affect processing in children and adolescents with autism spectrum disorder.

It is suggested that high-functioning individuals with ASD may be relatively unimpaired in the cognitive assessment of basic emotions, yet still show differences in the automatic processing of facial expressions.

The pathogenesis of autism: insights from congenital blindness.

  • R. HobsonM. Bishop
  • Psychology, Medicine
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 2003
If the authors can determine the way in which congenital blindness predisposes to features of autism, they shall be in a better position to trace the developmental pathways that lead to the syndrome in sighted children.

Social interest and the development of cortical face specialization: what autism teaches us about face processing.

Investigations of face processing in persons with an autism spectrum disorder (ASD) inform upon theories of the development of "normal" face processing, and the story that emerges challenges some

Abnormal ventral temporal cortical activity during face discrimination among individuals with autism and Asperger syndrome.

Individuals with autism spectrum disorders demonstrate a pattern of brain activity during face discrimination that is consistent with feature-based strategies that are more typical of nonface object perception.

A Normed Study of Face Recognition in Autism and Related Disorders

It is concluded that young children with autism have face recognition deficits that cannot be attributed to overall cognitive abilities or task demands.

The role of the fusiform face area in social cognition: implications for the pathobiology of autism.

In two linked functional magnetic resonance imaging studies of healthy young adults, it is shown that the FFA is engaged by a social attribution task (SAT) involving perception of human-like interactions among three simple geometric shapes.