Developmental defects of teeth in survivors of childhood ALL are related to the therapy and age at diagnosis.

@article{Pajari1995DevelopmentalDO,
  title={Developmental defects of teeth in survivors of childhood ALL are related to the therapy and age at diagnosis.},
  author={U H Pajari and Marjatta Lanning},
  journal={Medical and pediatric oncology},
  year={1995},
  volume={24 5},
  pages={
          310-4
        }
}
The relation of the therapy used and age at diagnosis to developmental defects of dental enamel and root was analyzed in 45 survivors of childhood acute lymphoblastic leukemia (ALL) and compared to that of age- and sex-matched healthy controls. Chemotherapy alone increased the number of enamel defects, but it did not affect the roots. The scattered irradiation of 0.72-1.44 Gy to the dental arches during central nervous system (CNS) irradiation caused an increased number of developmental defects… CONTINUE READING

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