Developmental competence and mRNA expression of preimplantation in vitro-produced embryos from prepubertal and postpubertal cattle and their relationship with apoptosis after intraovarian administration of IGF-1.

@article{Zaraza2010DevelopmentalCA,
  title={Developmental competence and mRNA expression of preimplantation in vitro-produced embryos from prepubertal and postpubertal cattle and their relationship with apoptosis after intraovarian administration of IGF-1.},
  author={J Zaraza and Azucena Oropeza and Miguel A. Mel{\'e}ndez Vel{\'a}zquez and Karin Korsawe and Doris Herrmann and Joseph Wallace Carnwath and Heiner Niemann},
  journal={Theriogenology},
  year={2010},
  volume={74 1},
  pages={75-89}
}
Recombinant human Insulin-like growth factor-I (hIGF-1) was administered to one ovary of prepubertal and postpubertal cattle to determine its effects on (1) oocyte developmental competence, (2) the expression pattern of six developmentally important genes (GLUT3, GLUT8, AKT1, BCL-XL, BAD, and BAX), and (3) its relationship with apoptosis (female Holstein-Friesian). Oocytes were retrieved from 7- to 10-mo-old prepubertal dairy calves (preP), 11- to 18-mo-old postpubertal heifers (postP), and… CONTINUE READING

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