Developmental checkpoints guarded by regulated necrosis

  title={Developmental checkpoints guarded by regulated necrosis},
  author={Christopher P Dillon and Bart Tummers and Katherine Baran and Douglas R Green},
  journal={Cellular and Molecular Life Sciences},
The process of embryonic development is highly regulated through the symbiotic control of differentiation and programmed cell death pathways, which together sculpt tissues and organs. The importance of programmed necrotic (RIPK-dependent necroptosis) cell death during development has recently been recognized as important and has largely been characterized… CONTINUE READING