Developmental changes in the umbilical arteries with observation of the effects of indomethacin in fetal rats.


The caliber of the umbilical arteries was measured in fetal rats on day 14 to 21 of gestation. The fetuses were rapidly frozen in an acetone-dry ice mixture. The caudal half of each whole-body frozen fetus was gradually shaved with a knife from the ventral side to expose the umbilical arteries for measurement of their calibers. Observation reveals that, on… (More)


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