Developmental changes in the subcellular localization of calretinin.

@article{Hack2000DevelopmentalCI,
  title={Developmental changes in the subcellular localization of calretinin.},
  author={Niklas Hack and Mark C Wride and K M Charters and Stanley B. Kater and Thomas N. Parks},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2000},
  volume={20 7},
  pages={
          RC67
        }
}
Brainstem auditory neurons in the chick nucleus magnocellularis (NM) express high levels of the neuron-specific calcium-binding protein calretinin (CR). CR has heretofore been considered a diffusible calcium buffer that is dispersed uniformly throughout the cytosol. Using high-resolution confocal microscopy and complementary biochemical analyses, we have found that during the development of NM neurons, CR changes from being expressed diffusely at low concentrations to being highly concentrated… CONTINUE READING

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