Developmental changes in the hypoxia tolerance of the in vitro respiratory network of rats.

Abstract

The functional relation between respiratory activity, extracellular potassium activity (aKe) and tissue oxygen pressure (pO2) was analyzed in vitro in the ventral respiratory group (VRG) of the neonatal brainstem-spinal cord (NB) and the perfused adult brainstem (AB) of rats. In the AB, an aKe increase of up to 35 mM and a reversible blockade of respiratory… (More)

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