Developmental changes in the expression of growth hormone-releasing hormone and pituitary adenylate cyclase-activating polypeptide in zebrafish.

@article{Krueckl2003DevelopmentalCI,
  title={Developmental changes in the expression of growth hormone-releasing hormone and pituitary adenylate cyclase-activating polypeptide in zebrafish.},
  author={Sandra L. Krueckl and Erica A Fradinger and Nancy McKeown Sherwood},
  journal={The Journal of comparative neurology},
  year={2003},
  volume={455 3},
  pages={396-405}
}
Growth hormone-releasing hormone (GHRH) and pituitary adenylate cyclase-activating polypeptide (PACAP) are structurally and functionally related members of the glucagon superfamily, a group of hormones important in development, growth, and metabolism. Our objectives were to determine the developmental expression pattern of the ghrh-pacap1 gene using the zebrafish model. The temporal and spatial expression pattern of the ghrh-pacap1 gene was examined by RT-PCR and in situ hybridization. In… CONTINUE READING
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