Developmental changes in the distribution of the endoplasmic reticulum and inositol 1,4,5-trisphosphate receptors and the spatial pattern of Ca2+ release during maturation of hamster oocytes.

@article{Shiraishi1995DevelopmentalCI,
  title={Developmental changes in the distribution of the endoplasmic reticulum and inositol 1,4,5-trisphosphate receptors and the spatial pattern of Ca2+ release during maturation of hamster oocytes.},
  author={Kyoko Shiraishi and Aya Okada and Hideki Shirakawa and Shigetada Nakanishi and Katsuhiko Mikoshiba and Shunichi Miyazaki},
  journal={Developmental biology},
  year={1995},
  volume={170 2},
  pages={594-606}
}
During maturation of hamster oocytes, the distribution of the endoplasmic reticulum (ER) and inositol 1,4,5-trisphosphate receptors (InsP3Rs) was found to change dramatically, as observed using confocal microscopy with DiI and electron microscopy for the ER and immunohistochemistry for InsP3Rs. In immature oocytes at the germinal vesicle (GV) stage, ER and InsP3Rs were located predominantly in several large masses near the surface and also in the perinuclear region near the surface. In contrast… CONTINUE READING