Developmental changes in response of dog isolated ventricular myocardium to norepinephrine.

Abstract

There are maturational changes of myocardial function and response to inotropic agents. Because of incomplete myocardial sympathetic innervation, neonatal myocardium may be more sensitive to norepinephrine than is adult myocardium. We tested this hypothesis by using isolated trabecular muscle from two groups of puppies and from adult dogs. The muscles were… (More)

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@article{Driscoll1983DevelopmentalCI, title={Developmental changes in response of dog isolated ventricular myocardium to norepinephrine.}, author={David J O ' Driscoll and I. S. Park and Paolo Baron and L. Michael}, journal={Texas Heart Institute journal}, year={1983}, volume={10 4}, pages={397-403} }