Developmental changes in hyperpolarization-activated currents I(h) and I(K(IR)) in isolated rat intracardiac neurons.

@article{Hogg2001DevelopmentalCI,
  title={Developmental changes in hyperpolarization-activated currents I(h) and I(K(IR)) in isolated rat intracardiac neurons.},
  author={R. C. Hogg and Alexander A. Harper and David J Adams},
  journal={Journal of neurophysiology},
  year={2001},
  volume={86 1},
  pages={312-20}
}
The hyperpolarization-activated nonselective cation current, I(h), was investigated in neonatal and adult rat intracardiac neurons. I(h) was observed in all neurons studied and displayed slow time-dependent rectification. I(h) was isolated by blockade with external Cs(+) (2 mM) and was inhibited irreversibly by the bradycardic agent, ZD 7288. Current density of I(h) was approximately twofold greater in neurons from neonatal (-4.1 pA/pF at -130 mV) as compared with adult (-2.3 pA/pF) rats… CONTINUE READING

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Properties of the hyperpolarization - activated cation current , I h , in neonatal and adult rat intracardiac neurons in vitro ( Abstract )

  • AA HARPER, RC HOGG, DJ ADAMS
  • J Physiol ( Lond )
  • 1998
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Inwardly rectifying K 1 current IK ( IR ) is present in juvenile but not in neonatal rat intracardiac neurons in vitro ( Abstract )

  • RC HOGG, AND ADAMS DJ HARPERAA
  • J Physiol ( Lond )
  • 1998

Substance P regulates I h via a NK1 receptor in vagal sensory neurons of the ferret

  • D JAFRIMSANDWEINRICH
  • J Neurophysiol
  • 1998

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