Developmental changes in Ca2+ channel subtypes regulating endocytosis at the calyx of Held.


At the mammalian central synapse, Ca(2+) influx through Ca(2+) channels triggers neurotransmitter release by exocytosis of synaptic vesicles, which fuse with the presynaptic membrane and are subsequently retrieved by endocytosis. At the calyx of Held terminal, P/Q-type Ca(2+) channels mainly mediate exocytosis, while N- and R-type channels have a minor role… (More)
DOI: 10.1113/jphysiol.2014.273243


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