Developmental change of GABAA receptor-mediated current in rat hippocampus

@article{Taketo2000DevelopmentalCO,
  title={Developmental change of GABAA receptor-mediated current in rat hippocampus},
  author={Megumi Taketo and Tohru Yoshioka},
  journal={Neuroscience},
  year={2000},
  volume={96},
  pages={507-514}
}

Development of GABA(A) receptor-mediated inhibitory postsynaptic currents in hippocampus.

TLDR
The rate, amplitude, and kinetics of GABA(A,fast) mIPSCs showed significant changes between P10 and P30, suggesting counterbalancing changes in action potential-dependent inhibitory postsynaptic currents in IPSCs, consistent with the hypothesis that developmental changes in GABA (A,slow) IPSCs are due to changes in presynaptic excitability.

Transition from GABAergic to glycinergic synaptic transmission in newly formed spinal networks.

TLDR
The role of glycinergic and GABAergic systems in mediating spontaneous synaptic transmission in newly formed neural networks was examined in motoneurons in the developing rat spinal cord, indicating that GABAergic synaptic sites were functionally dominant at early stages of neural network formation.

Sensitivity of synaptic GABAA receptors to allosteric modulators in hippocampal oriens‐alveus interneurons

TLDR
This pharmacological profile suggests that GABAA receptors at spontaneously active inhibitory synapses onto vertical and horizontal interneurons are heterogeneous and formed by co‐assembly of different combinations of subunits (α1–5β1–3γ1–4–3).

Differential pharmacological properties of GABAA receptors in axon terminals and soma of dentate gyrus granule cells

TLDR
The results suggest that the pharmacological properties of GABAA receptors differ considerably between presynaptic (axon terminals) and somatic regions in the same granule cell and thatPresynaptic GAB AA receptors should be considered as one of the important pharmacological targets of many drugs affecting GABaa receptors.

Differential Plasticity of the GABAergic and Glycinergic Synaptic Transmission to Rat Lumbar Motoneurons after Spinal Cord Injury

TLDR
It is concluded that the plasticity of GlyR is independent of supraspinal influences whereas that of GABAAR is markedly influenced by descending pathways, in particular serotoninergic projections.

Development and Modulation of GABAA Receptor-mediated Neurotransmission in the CA1 Region of Prenatally Protein Malnourished Rats

TLDR
Recordings of CA1 pyramidal cells demonstrate that the previously observed alterations in the serotonergic and GABAergic systems that result from prenatal protein malnutrition do not have significant functional consequences at a single cell level in the CA1 region of the rat hippocampus as measured in vitro.

Developmental and degenerative modulation of GABAergic transmission in the mouse hippocampus

...

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