Developmental cell biology: The cell biology of neurogenesis

@article{Gtz2005DevelopmentalCB,
  title={Developmental cell biology: The cell biology of neurogenesis},
  author={Magdalena G{\"o}tz and Wieland B. Huttner},
  journal={Nature Reviews Molecular Cell Biology},
  year={2005},
  volume={6},
  pages={777-788}
}
During the development of the mammalian central nervous system, neural stem cells and their derivative progenitor cells generate neurons by asymmetric and symmetric divisions. The proliferation versus differentiation of these cells and the type of division are closely linked to their epithelial characteristics, notably, their apical–basal polarity and cell-cycle length. Here, we discuss how these features change during development from neuroepithelial to radial glial cells, and how this… 
The cell biology of neurogenesis
  • W. Huttner
  • Biology
    International Journal of Developmental Neuroscience
  • 2006
Neurogenesis and asymmetric cell division
The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex.
TLDR
The issue of cell polarity is discussed, as well as specific subcellular features of these cells that are relevant for their modes of division and daughter cell fate, which help gain insight into key developmental and evolutionary mechanisms underlying neocortex expansion.
Drosophila neural stem cells: cell cycle control of self-renewal, differentiation, and termination in brain development.
  • H. Reichert
  • Biology
    Results and problems in cell differentiation
  • 2011
TLDR
Findings in Drosophila brain development are likely to have general relevance in neural stem cell biology and may apply to cell cycle control in mammalian brain development as well.
Regulation of self-renewal and differentiation in the Drosophila nervous system.
TLDR
The Drosophila nervous system has proved to be a fruitful model system for studying the biology of neural stem cell division and uncovering the molecular mechanisms that can lead to tumor formation.
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