Developmental cell biology: Developmental apoptosis in C. elegans: a complex CEDnario

  title={Developmental cell biology: Developmental apoptosis in C. elegans: a complex CEDnario},
  author={Guillaume Lettre and Michael O. Hengartner},
  journal={Nature Reviews Molecular Cell Biology},
Apoptosis, an evolutionarily conserved programme of cellular self-destruction, is essential for the development and survival of most multicellular animals. It is required to ensure functional organ architecture and to maintain tissue homeostasis. During development of the simple nematode Caenorhabditis elegans, apoptosis claims over 10% of the somatic cells that are generated ? these cells were healthy but unnecessary. Exciting insights into the regulation and execution of apoptosis in C… CONTINUE READING

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