Developmental capability of denuded bovine oocyte in a co-culture system with intact cumulus-oocyte complexes: role of cumulus cells, cyclic adenosine 3',5'-monophosphate, and glutathione.

@article{Luciano2005DevelopmentalCO,
  title={Developmental capability of denuded bovine oocyte in a co-culture system with intact cumulus-oocyte complexes: role of cumulus cells, cyclic adenosine 3',5'-monophosphate, and glutathione.},
  author={A. M. Luciano and Valentina Lodde and Matteo S Beretta and Silvia Colleoni and Antonio Lauria and Silvia Clotilde Modina},
  journal={Molecular reproduction and development},
  year={2005},
  volume={71 3},
  pages={389-97}
}
Cumulus oophorus cells have been implicated in the regulation of female gamete development, meiotic maturation, and oocyte-sperm interaction. Nevertheless, the specific role of cumulus cells (CCs) during the final stages of oocyte maturation and fertilization processes still remains unclear. Several studies have been conducted in order to clarify the role of follicular cells using culture systems where denuded oocytes (DOs) were co-cultured with isolated CCs, or in the presence of conditioned… CONTINUE READING

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