Developmental and transcriptional consequences of mutations in Drosophila TAF(II)60.

@article{Aoyagi2001DevelopmentalAT,
  title={Developmental and transcriptional consequences of mutations in Drosophila TAF(II)60.},
  author={Norikazu Aoyagi and David A Wassarman},
  journal={Molecular and cellular biology},
  year={2001},
  volume={21 20},
  pages={6808-19}
}
In vitro, the TAF(II)60 component of the TFIID complex contributes to RNA polymerase II transcription initiation by serving as a coactivator that interacts with specific activator proteins and possibly as a promoter selectivity factor that interacts with the downstream promoter element. In vivo roles for TAF(II)60 in metazoan transcription are not as clear… CONTINUE READING