Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1.

@article{Krumlauf1987DevelopmentalAS,
  title={Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1.},
  author={Robb K Krumlauf and Peter W H Holland and John H Mcvey and Brigid L. M. Hogan},
  journal={Development},
  year={1987},
  volume={99 4},
  pages={603-17}
}
The Hox 2.1 gene forms part of a cluster of homeobox-containing genes on mouse chromosome 11. Analysis of Hox 2.1 cDNAs isolated from an 8 1/2-day p.c. mouse embryo library predicts that the gene encodes a 269 amino acid protein (Mr, 29,432). This deduced protein contains a homeobox 15 amino acids from the carboxy terminus and is very rich in serine and proline. A second partially conserved region present in several other genes containing homeoboxes, the hexapeptide Ile-Phe-Pro-Trp-Met-Arg, is… CONTINUE READING