Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.

@article{Yabe2005DevelopmentalAR,
  title={Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.},
  author={Tomio Yabe and Toshihiro Hata and Jue He and Nobuaki Maeda},
  journal={Glycobiology},
  year={2005},
  volume={15 10},
  pages={982-93}
}
Heparan sulfate (HS) binds with various proteins including growth factors, morphogens, and extracellular matrix molecules to regulate their biological functions. These regulatory interactions are considered to be dependent on the structure of HS, which is determined by HS sulfotransferases. To gain insights into the functions of HS sulfotransferases in the development of the nervous system, we examined the expression of these enzymes (3-O-sulfotransferase-1 [3-OST-1], -2, -4; 6-OST-1, -2, -3… CONTINUE READING