Developmental and neurologic effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants.

@article{Bellinger2001DevelopmentalAN,
  title={Developmental and neurologic effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants.},
  author={D C David C Bellinger and David Wypij and A J du Plessis and Leonard A Rappaport and James Riviello and Richard A Jonas and Jane W. Newburger},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2001},
  volume={121 2},
  pages={374-83}
}
OBJECTIVES In a randomized single-center trial, we compared developmental and neurologic outcomes at 1 and 2 to 4 years of age in children who underwent reparative cardiac operations at less than 9 months of age after use of the alpha-stat versus pH-stat strategy during deep hypothermic cardiopulmonary bypass. METHODS Among 168 children eligible for follow-up, 1-year developmental evaluations were carried out on 111, neurologic evaluations on 110, and electroencephalographic evaluations on… CONTINUE READING
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