Developmental and cellular expression pattern of epithelial sodium channel alpha, beta and gamma subunits in the inner ear of the rat.

@article{Grnder2001DevelopmentalAC,
  title={Developmental and cellular expression pattern of epithelial sodium channel alpha, beta and gamma subunits in the inner ear of the rat.},
  author={Stefan Gr{\"u}nder and Anke Susanne M{\"u}ller and Johann Peter Ruppersberg},
  journal={The European journal of neuroscience},
  year={2001},
  volume={13 4},
  pages={641-8}
}
Endolymphatic ion composition in the adult inner ear is characterized by high K(+) and low Na(+) concentration. This unique ion composition is essential for proper functioning of sensory processing. Although a lot has been learned in recent years about molecules involved in K(+) transport in inner ear, the molecules involved in Na(+) transport are only beginning to emerge. The epithelial Na(+) channel (ENaC) is a highly selective Na(+) channel that is expressed in many Na(+)-reabsorbing tissues… CONTINUE READING

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