Developmental Expression of PEPT1 and PEPT2 in Rat Small Intestine, Colon, and Kidney

@article{Shen2001DevelopmentalEO,
  title={Developmental Expression of PEPT1 and PEPT2 in Rat Small Intestine, Colon, and Kidney},
  author={Hong Shen and David E Smith and Frank C. Brosius},
  journal={Pediatric Research},
  year={2001},
  volume={49},
  pages={789-795}
}
Mammalian peptide transporters (PEPT1 and PEPT2) play a pivotal role in the absorption of small peptides from the intestine and kidney, respectively, and in the disposition and targeting of peptide or mimetic drugs. However, there are few reports on the molecular basis of their regulation, especially in the young. The aim of this study was to determine the developmental expression of intestinal and renal oligopeptide transporters in rats from embryonic to adult ages. Intestinal segments were… CONTINUE READING

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