Developmental Coordination of Gene Expression between Synaptic Partners During GABAergic Circuit Assembly in Cerebellar Cortex

@inproceedings{Paul2012DevelopmentalCO,
  title={Developmental Coordination of Gene Expression between Synaptic Partners During GABAergic Circuit Assembly in Cerebellar Cortex},
  author={Anirban Paul and Ying Cai and Gurinder S. Atwal and Z. Josh Huang},
  booktitle={Front. Neural Circuits},
  year={2012}
}
The assembly of neural circuits involves multiple sequential steps such as the specification of cell-types, their migration to proper brain locations, morphological and physiological differentiation, and the formation and maturation of synaptic connections. This intricate and often prolonged process is guided by elaborate genetic mechanisms that regulate each step. Evidence from numerous systems suggests that each cell-type, once specified, is endowed with a genetic program that unfolds in… CONTINUE READING