Developmental Changes in the Expression of Kisspeptin mRNA in Rat Hypothalamus

@article{Takumi2010DevelopmentalCI,
  title={Developmental Changes in the Expression of Kisspeptin mRNA in Rat Hypothalamus},
  author={Ken Takumi and Norio Iijima and Hitoshi Ozawa},
  journal={Journal of Molecular Neuroscience},
  year={2010},
  volume={43},
  pages={138-145}
}
Kisspeptin is a family of neuropeptides and the natural ligands of G protein-coupled receptor (GPR)-54. Kisspeptin/GPR-54 system is known to play a pivotal role in puberty onset and in the regulation of reproductive functions. To clarify the postnatal ontogeny of kisspeptin neurons in rat hypothalamus, we analyzed the expression patterns of kisspeptin mRNA from neonate to adult by in situ hybridization. In anteroventral periventricular nucleus (AVPV), kisspeptin mRNA were first detected at… CONTINUE READING