Developmental Changes in Mechanical Responses and Receptor Subtypes


Endothelin-1 (ET-1) and endothelin-3 (ET-3) produced positive inotropic effects on electrically stimulated left atria and increased the frequency of spontaneously beating right atria of adult rats. The potency of the inotropic effect of ET-1 was greater than that of ET-3, but the potencies of the chronotropic effects of ET-1 and ET-3 were not significantly… (More)


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@inproceedings{Ishikawa2005DevelopmentalCI, title={Developmental Changes in Mechanical Responses and Receptor Subtypes}, author={Tomohisa Ishikawa and Liming Li and Osamu Shinmi and Sadao Kimura and Masashi Yanagisawa and Tomoh Masaki}, year={2005} }